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KMID : 0984920140160010056
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Journal of Skin Barrier Research
2014 Volume.16 No. 1 p.56 ~ p.63
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Assessment of Skin Barrier Function and Moisturizer Efficacy
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Hong Seung-Phil
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Abstract
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The stratum corneum (SC) serves as a main barrier for the skin, minimizing water loss andregulating absorption of substances. Transepidermal water loss (TEWL), based on the estimation of the water vapor gradient in the chamber, and skin hydration, reflects the water content of the SC, have been widely used to evaluate skin barrier function. Measurement of TEWL and hydration can also offer the possibility to monitor in vivo the effect of topical treatment in an objective and non-invasive way on the skin. Besides, many techniques are amenable to investigating its content and function of the barrier and the moisturizer. Here, I review the non-invasive methods employed to evaluate the function of skin barrier and the efficacy of moisturizer.
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KEYWORD
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Moisturizer efficacy, Skin barrier functional assessment, Transepidermal waterloss, Stratum corneum hydration
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